Nirmatrelvir-Ritonavir Results in Modest Reductions in COVID-19 Hospitalization and Death in Patients on Immunosuppressants
By Peter A. McCullough, MD, MPH Severe COVID-19 respiratory illness is partly characterized by cytokine storm or a hyper-immune response. A principle of treatment is to used corticosteroids, which are classic immunosuppressant drugs. Hence, the “immunocompromised” are not mechanistically at high risk for COVID-19 outcomes. The main issue of clinical concern is frailty, since those […]
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