USDA’s Mass H5N1 Poultry Vaccination Plan Likely to Rely on Leaky Zoetis H5N2 Vaccine

Jun 25th 2025 5:59pm EDT

By Nicolas Hulscher, MPH The USDA is preparing to authorize mass vaccination of chickens against H5N1 bird flu: The leading candidate appears to be the Zoetis vaccine targeting H5N2 — even though the dominant strain spreading through U.S. flocks is H5N1 clade 2.3.4.4b. The vaccine uses the N2 neuraminidase subtype deliberately to support DIVA (Differentiating […]

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