How Chronic Stress Increases Risk of Depression
STORY AT-A-GLANCE Chronic stress triggers a neutrophil invasion into brain-protective layers, driving depression-like behaviors through immune activation rather than just hormonal changes Stress-induced immune signals hijack brain reward circuits, reducing dopamine and shifting neural activity toward threat detection over pleasure-seeking behaviors Prolonged stress damages brain mitochondria, reducing cellular energy production while creating an inflammatory feedback […]
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